Web Lecture - McEwen - page 4 - slides # 19-24 |
Go to Slides #1-6, #7-12, #13-18, #19-24, #25-30, #31-36 , #37-41 |
"Sex, Stress and the Hippocampus: Receptors, Intracellular Mechanisms and Synaptic Plasticity" Bruce S. McEwen, PhD |
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Slide 19: Some human disorders where hippocampus is atrophied. Elevated glucocorticoid levels are implicated. Click for: AUDIO |
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Slide 20: In treatment of Cushing's disease, decreasing cortisol levels are correlated with increased hippocampal volume. i.e. hippo. atrophy is reversible. Click for: AUDIO |
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Slide 21: Depressive illness shows many of the same bodily changes as are seen in Cushing's disease. Click for: AUDIO |
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Slide 22: Hippocampal atrophy is correlated with length of depressive illness. Click for: AUDIO |
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Slide 23: In depression, hippo. atrophy may be accompanied by lesions or other damage. Autopsy data is needed to confirm this. Not clear whether this atrophy can be reversed. Click for: AUDIO |
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Slide 24: Possible causes of hippo. atrophy. Click for: AUDIO |
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